BPC-157 10mg Peptide Description

BPC-157 10mg is a research-grade synthetic pentadecapeptide supplied as a lyophilized powder in a single vial, intended exclusively for in-vitro laboratory studies on tissue repair, gastrointestinal integrity, angiogenesis, and neuroprotection. It is not approved for human or veterinary therapeutic use and is strictly for scientific research purposes.

Composition

• Active Ingredient: BPC-157 acetate (Body Protection Compound-157), a 15-amino-acid fragment (sequence: GEPPPGKPADDAGLV) derived from a protective protein found in human gastric juice.
• Purity: ≥99% by HPLC and mass spectrometry (third-party COA required for verification).
• Molecular Weight: 1,419.33 Da
• Molecular Formula: C₆₂H₉₈N₁₆O₂₂
• Form: Lyophilized white powder; highly stable in dry form.
• Storage:
  • Lyophilized: -20°C, desiccated, protected from light (stable 2+ years).
  • Reconstituted: 2–8°C for up to 4 weeks; avoid repeated freeze-thaw cycles.

The 10mg vial allows flexible dosing in preclinical models (typically 10–100 doses depending on concentration).

Mechanism of Action

BPC-157 acts as a signaling peptide with pleiotropic effects:

• Upregulates growth factors (VEGF, FGF, EGR-1) to promote angiogenesis and fibroblast migration.
• Modulates nitric oxide (NO) pathways, enhancing blood flow and tissue perfusion.
• Stabilizes gut-brain axis via serotonin and dopamine receptor interactions.
• Accelerates tendon-to-bone healing by increasing tenocyte proliferation and collagen organization.
• Exhibits anti-inflammatory effects by reducing pro-inflammatory cytokines (TNF-α, IL-6) without immunosuppression.

It is highly stable in gastric acid and shows systemic activity when administered subcutaneously, intramuscularly, or orally in animal models.

Research Applications

BPC-157 10mg is widely studied in preclinical models for: